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It is one potentially modifiable biochemical burden that may coexist with methylation imbalance, oxidative stress, copper-zinc dysregulation, pyroluria, gut dysfunction or immune activation

It is also available as a dietary supplement and is commonly used for relaxation, stress support, sleep quality and focus

Patients often use this blend for chronic pain, sports injuries, tendon damage, and post-operative healing

However, their growing numbers and intensive commercialisation in connection with new forms of tourism have raised concerns about how their development can be harmonised with national targets for environmental sustainability